Douglas Laboratories Riboflavin-5-Phosphate 10 mg. | Vitamin B2 Supports Energy Production, Cellular Respiration, Eyesight and Skin | 100 Capsules

Douglas Labs produces high quality supplements, of which this is one. B2, aka riboflavin, is a water soluble vitamin that can not be stored by the body. It has to be manufactured from food sources, mainly dairy and meat. People with a diet low in dairy or meat, or who have intestinal tract issues that interfere with absorption of nutrients from food, will tend to become deficient in all of the water soluble B vitamins. People over the age of 60 tend to produce less stomach acid that allows for adequate digestion of their food, so even on a good diet, they tend to become deficient in the B vitamins generally. Other causes of malabsorption are MTHFR mutations, such as I have, mold illness, aka Chronic Inflammatory Response Syndrome (CIRS) from which I am recovering, Crohn's disease, irritable bowel syndrome (IBS), and other disorders of the intestinal tract. Liver disease will also contribute to the inability to methylate or manufacture B vitamins. This is the activated, that is, bioavailable, form of riboflavin. That means that the body does not have to convert it further for it to be useable by cells. People like me with MTHFR mutations that screw up the methylation cycle not only tend to become very deficient in activated B12 and folate, that is, methylB12 and methylfolate and we tend to also become deficient in the other B vitamins such as R5P. That certainly was true for me. Even in people without MTHFR mutations, folate and Vitamin B6 (Pyridoxine) need R5P for conversion to their bioavailable forms, MTHF and P5P respectively. So if someone becomes deficient in R5P, for whatever reason, that cascades into deficiencies in MTHF and P5P. Low P5P is associated with breast cancer, particularly very aggressive breast cancers, per LEF studies. Symptoms of R5P deficiency include sores at the corners of the mouth, sore tongue, both of which I had with some frequency before starting R5P, dermatitis, numbness of the hands or decreased sensitivity to touch, temperature and vibration and visual changes, all of which this activated form of R5P will alleviate, while at the same time supporting adequate levels of MTHF and P5P.

I tend to need smaller doses of supplements and it's often hard to find them, especially in their active form. This 10mg supplement has really helped boost my mood and balance my B-vitamins out as I was low in B-2. No complaints, will order again!

I love this stuff! A friend told me about it for migraines. I take 8-10 capsules with a large glass of water and chill for about a half hour. Stops the migraine with no migraine hangover the next day. I keep a bottle at work and one in my purse. I wish I would have known about this years ago.

Pretty good product. I open the capsule to take half twice a day. The body won't absorb much more than that at once and the rest is excreted in urine. R5P is a 1:10 ratio so 10 mg is equal to about 100mg B2.

Bit lower price would be great. One can buy R5P powder in 25gr packages etc. So it would be great to see single B vitamins like these in low dosages to be priced better.

Was looking for a low dose of this vitamin, seemed pricey but this is the premium version, no complaints.

Purchased to even out ratios of methylated B complex vitamin product. Only company that produced small, reasonable sized dosage. Have used Douglas Lab. products previously. Satisfied here again.

I love Douglas Laboratories supplements and this is no exception. This brand was the most reasonably priced R5P supplement that I could find.