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Size:60 Capsules Everybody needs hormones to stay healthy; however, too much is unhealthy. This increase, called hormone Dominance, interferes with testosterone in men and leads to hormone imbalances in women. Symptoms of hormone Dominance: Women: PMS Weight gain Fibrocystic breasts Fibroids Endometriosis Abnormal menstruation Fatigue Reduced desire Depression Bloating Breast tenderness Mood swings Brain fog Insomnia Men: Enlarged breasts Reduced desire Abdominal weight gain Lethargy Fatigue Brain fog Insomnia Mood swings Irritability Depression Diindoylymethane (DIM) has potent effects on female hormone metabolism, it can inhibit the aromatase enzyme, prevent conversion of testosterone into female hormones and act on more potent forms of female hormones and convert them into less potent forms; this conversion reduces the overall effects of female hormones in the body. BioPerine® is a standardized Piperine composition derived from Black Pepper Extract and has been shown in clinical research to increase the absorption of nutrients in nutritional supplement formulations. In general, it was found to enhance absorption of nutrients by at least 30%. Broccoli Extract contains many phytochemicals that promote healthy metabolism of hormones, thereby reducing the negative side effects associated with female hormone dominance. Calcium D-Glucarate works by metabolizing an excess of female hormones in the body and helps the liver to metabolize hormones which is necessary for both males and females.