My Mom wears a size 22W, what size should I purchase for her?

Jessica I think it would be best if you could measure her waist and then go from there. Does she wear pants or dresses this could make a difference also. My cousin that wears these wears a XL and he weighs about 285 pounds and wears a 3XL pants, if that would help any.

We have an autistic grandson who is still not potty trained at the age of ten. He is a large boy and really needs a larger size of disposable pant?

I would most definitely try Amazon brand Solimo Unisex Underwear in M or XL. You don't want them to be loose fitting or they will leak around the inside leg. This brand is the same exact one as Prevail, Assurance and others. https://www.amazon.com/dp/B07B4Y37CW/ref=sspa_dk_detail_4?pd_rd_i=B07B4Y37CW&pd_rd_w=vPBAd&pf_rd_p=21517efd-b385-405b-a405-9a37af61b5b4&pd_rd_wg=6Tg5b&pf_rd_r=P8TGTSZB57X5JZEF851J&pd_rd_r=7b2445a3-2393-11e9-841b-4d76d22006a0&th=1

I purchase these for my mom...she loves them. She's wears the XXL and loves how they fit. She has tried other brands, but prefers the Prevail brand.

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💼 Stay sharp, stay dry — confidence that moves with you.

BULK VALUE PACK - 88 disposable pairs in 4 convenient packs—stock up and never run out of your essential protection.
SKIN FIRST COMFORT - Vitamin E, aloe & chamomile infused fabric plus breathable zones protect and soothe sensitive skin.
ODOR GUARD TECHNOLOGY - Advanced odor control neutralizes ammonia, so you stay fresh and worry-free.
UNMATCHED LEAK DEFENSE - Maximum absorbency with super absorbent polymers keeps you confidently dry all day.
DISCREET FLEXIBLE FIT - Comfort-Shape Plus gentle elastics contour to your body for a sleek, invisible profile under clothing.

Prevail Daily Protective Underwear offers unisex adult incontinence protection with maximum absorbency and a discreet, comfortable fit for waist sizes 20-34 inches. Featuring skin-friendly fabric infused with vitamin E, aloe, and chamomile, breathable zones to reduce heat buildup, and Odor Guard technology to neutralize odors, these disposable briefs provide all-day comfort and confidence. Each pack contains 88 pairs (4 packs of 22), designed for professional adults seeking reliable, skin-safe protection.